Llwytho...

The crystal structure of the major pneumococcal autolysin LytA in complex with a large peptidoglycan fragment reveals the pivotal role of glycans for lytic activity

The pneumococcal autolysin LytA is a key virulence factor involved in several important functions including DNA competence, immune evasion and biofilm formation. Here, we present the 1.05 Å crystal structure of the catalytic domain of LytA in complex with a synthetic cell-wall-based peptidoglycan (P...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Microbiol
Prif Awduron: Sandalova, Tatyana, Lee, Mijoon, Henriques-Normark, Birgitta, Hesek, Dusan, Mobashery, Shahriar, Mellroth, Peter, Achour, Adnane
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5014641/
https://ncbi.nlm.nih.gov/pubmed/27273793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13435
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!