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LytA, Major Autolysin of Streptococcus pneumoniae, Requires Access to Nascent Peptidoglycan
The pneumococcal autolysin LytA is a virulence factor involved in autolysis as well as in fratricidal- and penicillin-induced lysis. In this study, we used biochemical and molecular biological approaches to elucidate which factors control the cytoplasmic translocation and lytic activation of LytA. W...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3322828/ https://ncbi.nlm.nih.gov/pubmed/22334685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.318584 |
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