Structural and Functional Insights into Peptidoglycan Access for the Lytic Amidase LytA of Streptococcus pneumoniae

The cytosolic N-acetylmuramoyl-l-alanine amidase LytA protein of Streptococcus pneumoniae, which is released by bacterial lysis, associates with the cell wall via its choline-binding motif. During exponential growth, LytA accesses its peptidoglycan substrate to cause lysis only when nascent peptidog...

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Bibliographic Details
Main Authors: Mellroth, Peter, Sandalova, Tatyana, Kikhney, Alexey, Vilaplana, Francisco, Hesek, Dusan, Lee, Mijoon, Mobashery, Shahriar, Normark, Staffan, Svergun, Dmitri, Henriques-Normark, Birgitta, Achour, Adnane
Format: Artigo
Language:Inglês
Published: American Society of Microbiology 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3950521/
https://ncbi.nlm.nih.gov/pubmed/24520066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01120-13
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