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Conserved patterns hidden within group A Streptococcus M protein hypervariability are responsible for recognition of human C4b-binding protein
No vaccine exists against group A Streptococcus (GAS), a leading cause of worldwide morbidity and mortality. A severe hurdle is the hypervariability of its major antigen, the M protein, with >200 different M types known. Neutralizing antibodies typically recognize M protein hypervariable regions...
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| Publicado no: | Nat Microbiol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5014329/ https://ncbi.nlm.nih.gov/pubmed/27595425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmicrobiol.2016.155 |
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