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Streptococcal M1 protein constructs a pathological host fibrinogen network
M1 protein, a major virulence factor of the leading invasive strain of group A Streptococcus, is sufficient to induce toxic shock-like vascular leakage and tissue injury. These events are triggered by the formation of a complex between M1 and fibrinogen (Fg) that, unlike M1 or Fg alone, leads to neu...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3268815/ https://ncbi.nlm.nih.gov/pubmed/21475196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09967 |
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