Coiled-coil irregularities of the M1 protein structure promote M1–fibrinogen interaction and influence group A Streptococcus host cell interactions and virulence

Group A Streptococcus (GAS) is a human pathogen causing a wide range of mild to severe and life-threatening diseases. The GAS M1 protein is a major virulence factor promoting GAS invasiveness and resistance to host innate immune clearance. M1 displays an irregular coiled-coil structure, including th...

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Detalhes bibliográficos
Main Authors: Uchiyama, Satoshi, Andreoni, Federica, Zürcher, Claudia, Schilcher, Katrin, Ender, Miriam, Madon, Jerzy, Matt, Ulrich, Ghosh, Partho, Nizet, Victor, Schuepbach, Reto A., Zinkernagel, Annelies S.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3695690/
https://ncbi.nlm.nih.gov/pubmed/23443671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-013-1012-6
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