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Increased Neutrophil Extracellular Trap–Mediated Staphylococcus aureus Clearance Through Inhibition of Nuclease Activity by Clindamycin and Immunoglobulin

The Gram-positive human pathogen Staphylococcus aureus causes a variety of human diseases such as skin infections, pneumonia, and endocarditis. The micrococcal nuclease Nuc1 is one of the major S. aureus virulence factors and allows the bacterium to avoid neutrophil extracellular trap (NET)–mediated...

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Detalhes bibliográficos
Main Authors: Schilcher, Katrin, Andreoni, Federica, Uchiyama, Satoshi, Ogawa, Taiji, Schuepbach, Reto A., Zinkernagel, Annelies S.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4091580/
https://ncbi.nlm.nih.gov/pubmed/24526740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiu091
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