Increased Neutrophil Extracellular Trap–Mediated Staphylococcus aureus Clearance Through Inhibition of Nuclease Activity by Clindamycin and Immunoglobulin

The Gram-positive human pathogen Staphylococcus aureus causes a variety of human diseases such as skin infections, pneumonia, and endocarditis. The micrococcal nuclease Nuc1 is one of the major S. aureus virulence factors and allows the bacterium to avoid neutrophil extracellular trap (NET)–mediated...

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Bibliographic Details
Main Authors: Schilcher, Katrin, Andreoni, Federica, Uchiyama, Satoshi, Ogawa, Taiji, Schuepbach, Reto A., Zinkernagel, Annelies S.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2014
Subjects:
Major Articles and Brief Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4091580/
https://ncbi.nlm.nih.gov/pubmed/24526740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiu091
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