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Seizure suppression through manipulating splicing of a voltage-gated sodium channel
Seizure can result from increased voltage-gated persistent sodium current expression. Although many clinically-approved antiepileptic drugs target voltage-gated persistent sodium current, none exclusively repress this current without also adversely affecting the transient voltage-gated sodium curren...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Brain |
|---|---|
| Prif Awduron: | , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Oxford University Press
2015
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5014079/ https://ncbi.nlm.nih.gov/pubmed/25681415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awv012 |
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