Seizure suppression through manipulating splicing of a voltage-gated sodium channel

Seizure can result from increased voltage-gated persistent sodium current expression. Although many clinically-approved antiepileptic drugs target voltage-gated persistent sodium current, none exclusively repress this current without also adversely affecting the transient voltage-gated sodium curren...

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Bibliografiset tiedot
Julkaisussa:Brain
Päätekijät: Lin, Wei-Hsiang, He, Miaomiao, Baines, Richard A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2015
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Original Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5014079/
https://ncbi.nlm.nih.gov/pubmed/25681415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awv012
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