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Gene-set association tests for next-generation sequencing data

Motivation: Recently, many methods have been developed for conducting rare-variant association studies for sequencing data. These methods have primarily been based on gene-level associations but have not been proven to be as effective as expected. Gene-set-level tests have shown great advantages ove...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Bioinformatics
Main Authors: Lee, Jaehoon, Kim, Young Jin, Lee, Juyoung, Kim, Bong-Jo, Lee, Seungyeoun, Park, Taesung
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5013913/
https://ncbi.nlm.nih.gov/pubmed/27587681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw429
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