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Pathway-based approach using hierarchical components of collapsed rare variants
Motivation: To address ‘missing heritability’ issue, many statistical methods for pathway-based analyses using rare variants have been proposed to analyze pathways individually. However, neglecting correlations between multiple pathways can result in misleading solutions, and pathway-based analyses...
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| I publikationen: | Bioinformatics |
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| Huvudupphovsmän: | , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Oxford University Press
2016
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5013912/ https://ncbi.nlm.nih.gov/pubmed/27587678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw425 |
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