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The Synthetic Triterpenoid RTA 405 (CDDO-EA) Halts Progression of Liver Fibrosis and Reduces Hepatocellular Carcinoma Size Resulting in Increased Survival in an Experimental Model of Chronic Liver Injury

Patients with cirrhosis have an increased risk of developing liver cancer and a higher rate of mortality. Cirrhosis currently has no known cure, and patients may benefit from new agents aimed at alleviating their complications and slowing down the rate of disease progression. Therefore, the effects...

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Publicat a:Toxicol Sci
Autors principals: Getachew, Yonas, Cusimano, Frank A., Gopal, Purva, Reisman, Scott A., Shay, Jerry W.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5013822/
https://ncbi.nlm.nih.gov/pubmed/26443840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfv213
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