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The Synthetic Triterpenoid RTA 405 (CDDO-EA) Halts Progression of Liver Fibrosis and Reduces Hepatocellular Carcinoma Size Resulting in Increased Survival in an Experimental Model of Chronic Liver Injury

Patients with cirrhosis have an increased risk of developing liver cancer and a higher rate of mortality. Cirrhosis currently has no known cure, and patients may benefit from new agents aimed at alleviating their complications and slowing down the rate of disease progression. Therefore, the effects...

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Détails bibliographiques
Publié dans:Toxicol Sci
Auteurs principaux: Getachew, Yonas, Cusimano, Frank A., Gopal, Purva, Reisman, Scott A., Shay, Jerry W.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5013822/
https://ncbi.nlm.nih.gov/pubmed/26443840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfv213
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