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A large Rab GTPase encoded by CRACR2A is a component of novel subsynaptic vesicles that transmit T cell activation signals

More than 60 members of the Rab GTPase family exist in the human genome. However, our current understanding is only limited to the role of small Rab GTPases in membrane trafficking. Here we show that CRACR2A encodes a lymphocyte-specific “large Rab GTPase” containing multiple functional domains incl...

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Vydáno v:Sci Signal
Hlavní autoři: Srikanth, Sonal, Kim, Kyun-Do, Gao, Yuanyuan, Woo, Jin Seok, Ghosh, Shubhamoy, Calmettes, Guillaume, Paz, Aviv, Abramson, Jeff, Jiang, Meisheng, Gwack, Yousang
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5013727/
https://ncbi.nlm.nih.gov/pubmed/27016526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aac9171
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