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A novel EF-hand protein, CRACR2A, is a cytosolic Ca(2+) sensor that stabilizes CRAC channels in T cells
Orai1 and STIM1 are critical components of Ca(2+) release-activated Ca(2+) (CRAC) channels that mediate store-operated Ca(2+) entry (SOCE) in immune cells. While Orai1 and STIM1 co-cluster and physically interact to mediate SOCE, the cytoplasmic machinery modulating these functions remains poorly un...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2875865/ https://ncbi.nlm.nih.gov/pubmed/20418871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2045 |
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