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A large Rab GTPase encoded by CRACR2A is a component of novel subsynaptic vesicles that transmit T cell activation signals

More than 60 members of the Rab GTPase family exist in the human genome. However, our current understanding is only limited to the role of small Rab GTPases in membrane trafficking. Here we show that CRACR2A encodes a lymphocyte-specific “large Rab GTPase” containing multiple functional domains incl...

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Detalles Bibliográficos
Publicado en:Sci Signal
Main Authors: Srikanth, Sonal, Kim, Kyun-Do, Gao, Yuanyuan, Woo, Jin Seok, Ghosh, Shubhamoy, Calmettes, Guillaume, Paz, Aviv, Abramson, Jeff, Jiang, Meisheng, Gwack, Yousang
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5013727/
https://ncbi.nlm.nih.gov/pubmed/27016526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aac9171
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