Human primary airway epithelial cells isolated from active smokers have epigenetically impaired antiviral responses

BACKGROUND: Cigarette smoking (CS) is the main risk factor for the development of chronic obstructive pulmonary disease (COPD) and most COPD exacerbations are caused by respiratory infections including influenza. Influenza infections are more severe in smokers. The mechanism of the increased risk an...

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Bibliografische gegevens
Gepubliceerd in:Respir Res
Hoofdauteurs: Wu, Wenxin, Zhang, Wei, Booth, J. Leland, Hutchings, David C., Wang, Xiaoqiu, White, Vicky L., Youness, Houssein, Cross, Cory D., Zou, Ming-Hui, Burian, Dennis, Metcalf, Jordan P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2016
Onderwerpen:
Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5013564/
https://ncbi.nlm.nih.gov/pubmed/27604339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-016-0428-2
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