Human primary airway epithelial cells isolated from active smokers have epigenetically impaired antiviral responses

BACKGROUND: Cigarette smoking (CS) is the main risk factor for the development of chronic obstructive pulmonary disease (COPD) and most COPD exacerbations are caused by respiratory infections including influenza. Influenza infections are more severe in smokers. The mechanism of the increased risk an...

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Библиографические подробности
Опубликовано в: :Respir Res
Главные авторы: Wu, Wenxin, Zhang, Wei, Booth, J. Leland, Hutchings, David C., Wang, Xiaoqiu, White, Vicky L., Youness, Houssein, Cross, Cory D., Zou, Ming-Hui, Burian, Dennis, Metcalf, Jordan P.
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2016
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5013564/
https://ncbi.nlm.nih.gov/pubmed/27604339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-016-0428-2
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