Human primary airway epithelial cells isolated from active smokers have epigenetically impaired antiviral responses

BACKGROUND: Cigarette smoking (CS) is the main risk factor for the development of chronic obstructive pulmonary disease (COPD) and most COPD exacerbations are caused by respiratory infections including influenza. Influenza infections are more severe in smokers. The mechanism of the increased risk an...

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: Wu, Wenxin, Zhang, Wei, Booth, J. Leland, Hutchings, David C., Wang, Xiaoqiu, White, Vicky L., Youness, Houssein, Cross, Cory D., Zou, Ming-Hui, Burian, Dennis, Metcalf, Jordan P.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5013564/
https://ncbi.nlm.nih.gov/pubmed/27604339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-016-0428-2
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