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The Role of Type I IFNs in Influenza: Antiviral Superheroes or Immunopathogenic Villains?

The important role of interferons (IFNs) in antiviral innate immune defense is well established. Although recombinant IFN-α was approved for cancer and chronic viral infection treatment by regulatory agencies in many countries starting in 1986, no IFNs are approved for treatment of influenza A virus...

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Bibliographic Details
Published in:J Innate Immun
Main Authors: Wu, Wenxin, Metcalf, Jordan P.
Format: Artigo
Language:Inglês
Published: S. Karger AG 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7747089/
https://ncbi.nlm.nih.gov/pubmed/32564033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000508379
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