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High Levels of Transcription Stimulate Transversions at GC Base Pairs in Yeast

High-levels of transcription through a gene stimulate spontaneous mutation rate, a phenomenon termed transcription-associated mutation (TAM). While transcriptional effects on specific mutation classes have been identified using forward mutation and frameshift-reversion assays, little is yet known ab...

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Dades bibliogràfiques
Publicat a:Environ Mol Mutagen
Autors principals: Alexander, Matthew P., Begins, Kaitlyn J., Crall, William C., Holmes, Margaret P., Lippert, Malcolm J.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5013542/
https://ncbi.nlm.nih.gov/pubmed/23055242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.21740
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