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TRANSCRIPTION-ASSOCIATED MUTAGENESIS IN YEAST IS DIRECTLY PROPORTIONAL TO THE LEVEL OF GENE EXPRESSION AND INFLUENCED BY THE DIRECTION OF DNA REPLICATION
A high level of transcription has been associated with elevated spontaneous mutation and recombination rates in eukaryotic organisms. To determine whether the transcription level is directly correlated with the degree of genomic instability, we have developed a tetracycline-regulated LYS2 reporter s...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2007
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2034516/ https://ncbi.nlm.nih.gov/pubmed/17398168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2007.02.023 |
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