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Guanine repeat-containing sequences confer transcription-dependent instability in an orientation-specific manner in yeast
Non-B DNA structures are a major contributor to the genomic instability associated with repetitive sequences. Immunoglobulin switch Mu (Sμ) region sequence is comprised of guanine-rich repeats and has high potential for forming G4 DNA, in which one strand of DNA folds into an array of guanine quarte...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3162091/ https://ncbi.nlm.nih.gov/pubmed/21813340 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2011.07.002 |
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