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Guanine repeat-containing sequences confer transcription-dependent instability in an orientation-specific manner in yeast

Non-B DNA structures are a major contributor to the genomic instability associated with repetitive sequences. Immunoglobulin switch Mu (Sμ) region sequence is comprised of guanine-rich repeats and has high potential for forming G4 DNA, in which one strand of DNA folds into an array of guanine quarte...

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Detalhes bibliográficos
Main Authors: Kim, Nayun, Jinks-Robertson, Sue
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162091/
https://ncbi.nlm.nih.gov/pubmed/21813340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2011.07.002
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