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Transcription as a source of genome instability

Alterations in genome sequence and structure contribute to somatic disease, affect the fitness of subsequent generations and drive evolutionary processes. The critical roles of highly accurate replication and efficient repair in maintaining overall genome integrity are well known, but the more local...

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Detalhes bibliográficos
Main Authors: Kim, Nayun, Jinks-Robertson, Sue
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376450/
https://ncbi.nlm.nih.gov/pubmed/22330764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrg3152
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