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Transcription as a source of genome instability

Alterations in genome sequence and structure contribute to somatic disease, affect the fitness of subsequent generations and drive evolutionary processes. The critical roles of highly accurate replication and efficient repair in maintaining overall genome integrity are well known, but the more local...

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Autors principals: Kim, Nayun, Jinks-Robertson, Sue
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376450/
https://ncbi.nlm.nih.gov/pubmed/22330764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrg3152
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