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The Top1 paradox: Friend and foe of the eukaryotic genome
Topoisomerases manage the torsional stress associated with the separation of DNA strands during transcription and DNA replication. Eukaryotic Topoisomerase I (Top1) is a Type IB enzyme that nicks and rejoins only one strand of duplex DNA, and it is especially important during transcription. By resol...
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| Publicado no: | DNA Repair (Amst) |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5560766/ https://ncbi.nlm.nih.gov/pubmed/28641942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2017.06.005 |
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