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Identification of a Distinctive Mutation Spectrum Associated with High Levels of Transcription in Yeast
High levels of transcription are associated with increased mutation rates in Saccharomyces cerevisiae, a phenomenon termed transcription-associated mutation (TAM). To obtain insight into the mechanism of TAM, we obtained LYS2 forward mutation spectra under low- versus high-transcription conditions i...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2004
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC416428/ https://ncbi.nlm.nih.gov/pubmed/15143174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.11.4801-4809.2004 |
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