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High Levels of Transcription Stimulate Transversions at GC Base Pairs in Yeast
High-levels of transcription through a gene stimulate spontaneous mutation rate, a phenomenon termed transcription-associated mutation (TAM). While transcriptional effects on specific mutation classes have been identified using forward mutation and frameshift-reversion assays, little is yet known ab...
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| Veröffentlicht in: | Environ Mol Mutagen |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5013542/ https://ncbi.nlm.nih.gov/pubmed/23055242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.21740 |
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