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A biosensor for the protease TACE reveals actin damage induced TACE activation

Ligand shedding has gained increased attention as a major posttranslational modification mechanism used by cells to respond to diverse environmental conditions. The TACE(adam17) protease is a critical mediator of such ligand shedding, regulating the maturation and release of an impressive range of e...

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Detalhes bibliográficos
Publicado no:Sci Signal
Main Authors: Chapnick, Douglas A., Bunker, Eric, Liu, Xuedong
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012641/
https://ncbi.nlm.nih.gov/pubmed/25714465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2005680
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