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Analysis of Ligand Dependent Nuclear Accumulation of Smads in TGF-beta Signaling
The growth inhibition of dividing cells and most of the transcriptional responses upon TGF-beta treatment depend on the Smad2, Smad3, and Smad4 transcription factors. These proteins shuttle continuously between the cytoplasm and the nucleus, transmitting the ligand status of the TGF-beta receptors t...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4083701/ https://ncbi.nlm.nih.gov/pubmed/20694662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-60761-738-9_5 |
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