Retinoids regulate TGFβ signaling at the level of Smad2 phosphorylation and nuclear accumulation

Indirect regulation of transforming growth factor (TGF)-β signaling by retinoids occurs on a long-term timescale, secondary to transcriptional events. Studies by our group show loss of retinoid X receptor (RXR) alpha results in increased TGFβ2 in the midgestational heart, which may play a role in th...

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Autores principales: Hoover, Loretta L., Burton, Elizabeth G., O'Neill, Megan L., Brooks, Bonnie A., Sreedharan, Shilpa, Dawson, Nineveh A., Kubalak, Steven W.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596883/
https://ncbi.nlm.nih.gov/pubmed/18773928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2008.07.028
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