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Suppression of α-catenin and adherens junctions enhances epithelial cell proliferation and motility via TACE-mediated TGF-α autocrine/paracrine signaling

Sustained cell migration is essential for wound healing and cancer metastasis. The epidermal growth factor receptor (EGFR) signaling cascade is known to drive cell migration and proliferation. While the signal transduction downstream of EGFR has been extensively investigated, our knowledge of the in...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Bunker, Eric N., Wheeler, Graycen E., Chapnick, Douglas A., Liu, Xuedong
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8098817/
https://ncbi.nlm.nih.gov/pubmed/33378218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E19-08-0474
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