An Autoinhibited Structure of α-Catenin and Its Implications for Vinculin Recruitment to Adherens Junctions

α-Catenin is an actin- and vinculin-binding protein that regulates cell-cell adhesion by interacting with cadherin adhesion receptors through β-catenin, but the mechanisms by which it anchors the cadherin-catenin complex to the actin cytoskeleton at adherens junctions remain unclear. Here we determi...

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Main Authors: Ishiyama, Noboru, Tanaka, Nobutoshi, Abe, Kentaro, Yang, Yoo Jeong, Abbas, Yazan M., Umitsu, Masataka, Nagar, Bhushan, Bueler, Stephanie A., Rubinstein, John L., Takeichi, Masatoshi, Ikura, Mitsuhiko
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2013
主題:
Cell Biology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668747/
https://ncbi.nlm.nih.gov/pubmed/23589308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.453928
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