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Leader cell positioning drives wound-directed collective migration in TGFβ-stimulated epithelial sheets

During wound healing and cancer metastasis, cells are frequently observed to migrate in collective groups. This mode of migration relies on the cooperative guidance of leader and follower cells throughout the collective group. The upstream determinants and molecular mechanisms behind such cellular g...

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Detalhes bibliográficos
Main Authors: Chapnick, Douglas A., Liu, Xuedong
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019490/
https://ncbi.nlm.nih.gov/pubmed/24623725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-01-0697
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