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Leader cell positioning drives wound-directed collective migration in TGFβ-stimulated epithelial sheets

During wound healing and cancer metastasis, cells are frequently observed to migrate in collective groups. This mode of migration relies on the cooperative guidance of leader and follower cells throughout the collective group. The upstream determinants and molecular mechanisms behind such cellular g...

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Библиографические подробности
Главные авторы: Chapnick, Douglas A., Liu, Xuedong
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Cell Biology 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019490/
https://ncbi.nlm.nih.gov/pubmed/24623725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-01-0697
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