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Empirical Bayes Estimation of Coalescence Times from Nucleotide Sequence Data

We demonstrate the advantages of using information at many unlinked loci to better calibrate estimates of the time to the most recent common ancestor (TMRCA) at a given locus. To this end, we apply a simple empirical Bayes method to estimate the TMRCA. This method is both asymptotically optimal, in...

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Bibliografiske detaljer
Udgivet i:Genetics
Main Authors: King, Leandra, Wakeley, John
Format: Artigo
Sprog:Inglês
Udgivet: Genetics Society of America 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012390/
https://ncbi.nlm.nih.gov/pubmed/27440864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.115.185751
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