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Gene Genealogies Within a Fixed Pedigree, and the Robustness of Kingman’s Coalescent

We address a conceptual flaw in the backward-time approach to population genetics called coalescent theory as it is applied to diploid biparental organisms. Specifically, the way random models of reproduction are used in coalescent theory is not justified. Instead, the population pedigree for diploi...

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Main Authors: Wakeley, John, King, Léandra, Low, Bobbi S., Ramachandran, Sohini
格式: Artigo
語言:Inglês
出版: Genetics Society of America 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3316654/
https://ncbi.nlm.nih.gov/pubmed/22234858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.111.135574
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