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Gene Genealogies Within a Fixed Pedigree, and the Robustness of Kingman’s Coalescent

We address a conceptual flaw in the backward-time approach to population genetics called coalescent theory as it is applied to diploid biparental organisms. Specifically, the way random models of reproduction are used in coalescent theory is not justified. Instead, the population pedigree for diploi...

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Detalhes bibliográficos
Main Authors: Wakeley, John, King, Léandra, Low, Bobbi S., Ramachandran, Sohini
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3316654/
https://ncbi.nlm.nih.gov/pubmed/22234858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.111.135574
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