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Empirical Bayes Estimation of Coalescence Times from Nucleotide Sequence Data

We demonstrate the advantages of using information at many unlinked loci to better calibrate estimates of the time to the most recent common ancestor (TMRCA) at a given locus. To this end, we apply a simple empirical Bayes method to estimate the TMRCA. This method is both asymptotically optimal, in...

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Publicat a:Genetics
Autors principals: King, Leandra, Wakeley, John
Format: Artigo
Idioma:Inglês
Publicat: Genetics Society of America 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012390/
https://ncbi.nlm.nih.gov/pubmed/27440864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.115.185751
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