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Frequentist estimation of coalescence times from nucleotide sequence data using a tree-based partition.

This article proposes a method of estimating the time to the most recent common ancestor (TMRCA) of a sample of DNA sequences. The method is based on the molecular clock hypothesis, but avoids assumptions about population structure. Simulations show that in a wide range of situations, the point esti...

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Detalhes bibliográficos
Main Authors: Tang, Hua, Siegmund, David O, Shen, Peidong, Oefner, Peter J, Feldman, Marcus W
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1462078/
https://ncbi.nlm.nih.gov/pubmed/12019257
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