Antibody to FcεRIα Suppresses Immunoglobulin E Binding to High-Affinity Receptor I in Allergic Inflammation

PURPOSE: High-affinity receptor I (FcεRI) on mast cells and basophils plays a key role in the immunoglobulin E (IgE)-mediated type I hypersensitivity mediated by allergen cross-linking of the specific IgE-FcεRI complex. Thus, prevention of IgE binding to FcεRI on these cells is an effective therapy...

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Pubblicato in:Yonsei Med J
Autori principali: Hong, Jung Yeon, Bae, Jong-Hwan, Lee, Kyung Eun, Kim, Mina, Kim, Min Hee, Kang, Hyun Jung, Park, Eun Hye, Yoo, Kyung Sook, Jeong, Se Kyoo, Kim, Kyung Won, Kim, Kyu-Earn, Sohn, Myung Hyun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Yonsei University College of Medicine 2016
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5011273/
https://ncbi.nlm.nih.gov/pubmed/27593869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3349/ymj.2016.57.6.1412
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