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GMP reductase and genetic uncoupling of adenylate and guanylate metabolism in Leishmania donovani parasites

Purine acquisition is an essential nutritional process for Leishmania. Although purine salvage into adenylate nucleotides has been investigated in detail, little attention has been focused on the guanylate branch of the purine pathway. To characterize guanylate nucleotide metabolism in Leishmania an...

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Veröffentlicht in:Mol Biochem Parasitol
Hauptverfasser: Boitz, Jan M., Jardim, Armando, Ullman, Buddy
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010971/
https://ncbi.nlm.nih.gov/pubmed/27343371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbiopara.2016.06.008
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