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The Cystathionine-β-synthase Domains on the Guanosine 5′-Monophosphate Reductase and Inosine 5′-Monophosphate Dehydrogenase Enzymes from Leishmania Regulate Enzymatic Activity in Response to Guanylate and Adenylate Nucleotide Levels
The Leishmania guanosine 5′-monophosphate reductase (GMPR) and inosine 5′-monophosphate dehydrogenase (IMPDH) are purine metabolic enzymes that function maintaining the cellular adenylate and guanylate nucleotide. Interestingly, both enzymes contain a cystathionine-β-synthase domain (CBS). To invest...
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| izdano v: | Mol Microbiol |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4879609/ https://ncbi.nlm.nih.gov/pubmed/26853689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13352 |
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