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Purine salvage in Leishmania: complex or simple by design?

Purine nucleotides function in a variety of vital cellular and metabolic processes including energy production, cell signaling, synthesis of vitamin-derived cofactors and nucleic acids, and as determinants of cell fate. Unlike their mammalian and insect hosts, Leishmania cannot synthesize the purine...

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Détails bibliographiques
Auteurs principaux: Boitz, Jan M., Ullman, Buddy, Jardim, Armando, Carter, Nicola S.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429121/
https://ncbi.nlm.nih.gov/pubmed/22726696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pt.2012.05.005
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