Adenine Aminohydrolase from Leishmania donovani: UNIQUE ENZYME IN PARASITE PURINE METABOLISM

Adenine aminohydrolase (AAH) is an enzyme that is not present in mammalian cells and is found exclusively in Leishmania among the protozoan parasites that infect humans. AAH plays a paramount role in purine metabolism in this genus by steering 6-aminopurines into 6-oxypurines. Leishmania donovani AA...

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Bibliographic Details
Main Authors: Boitz, Jan M., Strasser, Rona, Hartman, Charles U., Jardim, Armando, Ullman, Buddy
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2012
Subjects:
Metabolism
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293595/
https://ncbi.nlm.nih.gov/pubmed/22238346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.307884
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