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Adenine Aminohydrolase from Leishmania donovani: UNIQUE ENZYME IN PARASITE PURINE METABOLISM

Adenine aminohydrolase (AAH) is an enzyme that is not present in mammalian cells and is found exclusively in Leishmania among the protozoan parasites that infect humans. AAH plays a paramount role in purine metabolism in this genus by steering 6-aminopurines into 6-oxypurines. Leishmania donovani AA...

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Detalles Bibliográficos
Main Authors: Boitz, Jan M., Strasser, Rona, Hartman, Charles U., Jardim, Armando, Ullman, Buddy
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293595/
https://ncbi.nlm.nih.gov/pubmed/22238346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.307884
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