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Immunotherapy expands and maintains the function of high affinity tumor infiltrating CD8 T cells in situ
Cancer cells harbor high affinity tumor-associated antigens capable of eliciting potent anti-tumor T cell responses yet detecting these polyclonal T cells is challenging. Therefore, surrogate markers of T cell activation such as CD69, CD44, and PD-1 have been used. We report here that in mice, expre...
Enregistré dans:
| Publié dans: | J Immunol |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5010950/ https://ncbi.nlm.nih.gov/pubmed/27503208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502659 |
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