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Immunotherapy expands and maintains the function of high affinity tumor infiltrating CD8 T cells in situ

Cancer cells harbor high affinity tumor-associated antigens capable of eliciting potent anti-tumor T cell responses yet detecting these polyclonal T cells is challenging. Therefore, surrogate markers of T cell activation such as CD69, CD44, and PD-1 have been used. We report here that in mice, expre...

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Bibliografiska uppgifter
I publikationen:J Immunol
Huvudupphovsmän: Moran, Amy E., Polesso, Fanny, Weinberg, Andrew D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010950/
https://ncbi.nlm.nih.gov/pubmed/27503208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502659
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