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Generation of highly activated, antigen-specific tumor-infiltrating CD8(+) T cells induced by a novel T cell-targeted immunotherapy

The induction of tumor-targeted, cytotoxic T lymphocytes has been recognized as a key component to successful immunotherapy. DPX-based treatment was previously shown to effectively recruit activated CD8(+) T cells to the tumor. Herein, we analyze the unique phenotype of the CD8(+) T cells recruited...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Vila-Leahey, Ava, MacKay, Alecia, Portales-Cervantes, Liliana, Weir, Genevieve M., Merkx-Jacques, Alexandra, Stanford, Marianne M.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7458631/
https://ncbi.nlm.nih.gov/pubmed/32923145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2020.1782574
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